A next-generation sterile wound care solution powered by bioengineered human collagen Type III. Designed to support rapid skin regeneration, this medical dressing accelerates healing, soothes inflammation, and helps minimize scarring for a smoother, more resilient recovery. Ideal for post-aesthetic procedures, burns, minor wounds, and damaged sensitive skin. Safe, non-irritating, and hormone-free—suitable for all skin types, including sensitive and compromised skin.
Product Suitable for
Cosmetic Surgery Clinic/Hospital, Aesthetic Plastic Surgery Center, Plastic Surgery Center, Aesthetic Medicine Institute, etc.
Images
The relevant research has been published in a paper and accepted by Burns, a top international journal in the field of burns.
The patch is made of fresh skin tissue from standardized Bama miniature pigs and is made by high-tech means based on the theory of cell activation co-stimulation immune tolerance and gene transfection technology. This product can effectively cover the burn wound for a longer period of time and provide active growth factors. It is a new type of active biological dressing for the effective treatment of burns and other wounds.
1. Compared with the blank control group, the collagen fiber content in the negative control group was significantly reduced, indicating that the stimulation conditions of this experiment were effective.
2. Compared with the negative control group, the collagen fiber content in the positive control group was significantly increased, indicating that the positive control test was effective.
3. Recollagen with a concentration of 0.2% significantly increased the collagen fiber content.
Experimental conclusion: After adding Recollagen recombinant collagen to the SLS damaged skin model, collagen has a significant penetration phenomenon, indicating that Recollagen can enter the stratum corneum of the damaged skin epidermis and may continue to penetrate into the tissue to repair the skin barrier.
1. Skin barrier-related genes (LOR, TGM1) were significantly overexpressed (p<0.05), indicating that recombinant collagen has the effect of repairing keratin and maintaining keratin integrity.
2. Natural moisturizing factor-related genes (FLG, Caspase-14) were significantly overexpressed (p<0.05), indicating that recombinant collagen has good moisturizing effect.
3. Cytoskeleton protein gene (K16) was significantly overexpressed (p<0.05), indicating that recombinant collagen plays a role in promoting keratinocyte differentiation and skin renewal.
4. The increased expression of sebum-related genes (ABCA12, ACACA, HMGCR) and cell junction protein-related genes (OCLN1, DSG1) indicates that recombinant collagen plays a role in maintaining normal skin function.
Publications
Key Factors
1mL/bottle, 1.5mL/bottle, 2mL/bottle, 3mL/bottle, 5mL/bottle, 6mL/bottle, 8mL/bottle, 10mL/bottle, 12mL/bottle, 15mL/bottle, 18mL/bottle, 20mL/bottle, 25mL/bottle, 30mL/bottle, 35mL/bottle, 40mL/bottle, 45mL/bottle, 50mL/bottle, 60mL/bottle, 70mL/bottle, 80mL/bottle, 90mL/bottle, 100mL/bottle, 110mL/bottle, 120mL/bottle, 150mL/bottle, 180mL/bottle, 200mL/bottle, 250mL/bottle
more can contact for customisation.
1. Spray Type
2. Gel Type
Cool and dry place
Suitable Wound Condition
View All Suitable Wounds
Suitable Hospital Department
This product is suitable for the care of non-chronic wounds (such as superficial wounds, wounds sutured after surgery, mechanical trauma, small wounds, abrasions, cut wounds, puncture sites of puncture instruments, first-degree or shallow second-degree burn wounds, laser/photon/acid peel/micro-plastic surgery wounds, etc.), providing a microenvironment for wound healing. This product is sterilized by irradiation and is supplied sterile.
Key Factors
The product consists of recombinant type III collagen stock solution, medical polyethylene bottle or medical resin bottle. The recombinant type III collagen stock solution mainly consists of recombinant type III humanized collagen, sodium propylparaben and purified water.
1. Spray Type
2. Gel Type
Cool and dry place, avoid sunlight.
1mL/bottle, 1.5mL/bottle, 2mL/bottle, 3mL/bottle, 5mL/bottle, 6mL/bottle, 8mL/bottle, 10mL/bottle, 12mL/bottle, 15mL/bottle, 18mL/bottle, 20mL/bottle, 25mL/bottle, 30mL/bottle, 35mL/bottle, 40mL/bottle, 45mL/bottle, 50mL/bottle, 60mL/bottle, 70mL/bottle, 80mL/bottle, 90mL/bottle, 100mL/bottle, 110mL/bottle, 120mL/bottle, 150mL/bottle, 180mL/bottle, 200mL/bottle, 250mL/bottle
more can contact for customisation.
2 Years
Directions
Contraindications
- It is contraindicated for those who are allergic to any ingredient of this product;
- Pregnant women, breastfeeding women, infants and young children should use it under the guidance of a doctor;
- It should be used under the guidance of a doctor for suppurative wounds;
- It is contraindicated for those who are allergic to raw materials, and should be used with caution for those with unclear allergies. If you feel unwell, please stop using it immediately or follow the doctor’s advice;
- It is not suitable for patients with wound infection.
Precautions
- This product is a sterile external product, please do not take it orally;
- Do not use if the inner packaging is broken;
- Please read the instructions carefully before use, and do not use it after the expiration date;
- Please keep it out of reach of children;
- During use, if allergic symptoms occur, stop using it immediately and consult a doctor in time;
- This product cannot replace medicine. If used with other treatments or medicines, please consult a professional doctor;
- After opening the package of type I products, it is recommended to use it within 30 days; type II products are for one-time use;
- If there are symptoms such as redness, swelling, pain or itching during use, please stop using it immediately and wash it clean. If necessary, consult a doctor or seek medical treatment in time;
- The user group is infants, children, adults and the elderly.
Recombinant Human Collagen III Safety Evaluation
Recombinant Human Collagen III Repair Ability Assessment
Experimental conclusion: Through the HACAT cell in vitro cell migration test, it can be intuitively found that Recollagen has a significant promoting effect on cell migration, suggesting that it has the function of tissue damage repair.
Damaged Skin Model Repair Experiment
Experimental principle: Use chemically induced 3D skin models to simulate damaged skin models, detect the penetration of Recollagen recombinant collagen in damaged 3D skin models, and simulate whether active substances in damaged skin can penetrate and take effect.
Experimental conclusion: After adding Recollagen recombinant collagen to the SLS damaged skin model, collagen has a significant penetration phenomenon, indicating that Recollagen can enter the stratum corneum of the damaged skin epidermis and may continue to penetrate into the tissue to repair the skin barrier.
World Health Organization (WHO) Registered Clinical Research
Registration number：ChiCTR1900023998
The relevant research has been published in a paper and accepted by Burns, a top international journal in the field of burns.
The patch is made of fresh skin tissue from standardized Bama miniature pigs and is made by high-tech means based on the theory of cell activation co-stimulation immune tolerance and gene transfection technology. This product can effectively cover the burn wound for a longer period of time and provide active growth factors. It is a new type of active biological dressing for the effective treatment of burns and other wounds.
Detection Of the Effect of Recollagen on Epidermal Cell Differentiation at The Genetic Level
Experimental results:
- Skin barrier-related genes (LOR, TGM1) were significantly overexpressed (p<0.05), indicating that recombinant collagen has the effect of repairing keratin and maintaining keratin integrity.
- Natural moisturizing factor-related genes (FLG, Caspase-14) were significantly overexpressed (p<0.05), indicating that recombinant collagen has good moisturizing effect.
- Cytoskeleton protein gene (K16) was significantly overexpressed (p<0.05), indicating that recombinant collagen plays a role in promoting keratinocyte differentiation and skin renewal.
- The increased expression of sebum-related genes (ABCA12, ACACA, HMGCR) and cell junction protein-related genes (OCLN1, DSG1) indicates that recombinant collagen plays a role in maintaining normal skin function.
Comparison Of Clinical Efficacy Between The Two Groups Under White Light And Polarized Light Sources
Anti-Aging Ability Assessment 1
Experimental principle: For Ex vivo skin tissue, a UVA+UVB combined induction system that simulates natural light is used. The Masson staining experiment is used to observe the changes in collagen fibers in the skin tissue model and whether Recollagen in the skin model can promote the formation of collagen fibers.
Experimental results:
- Compared with the blank control group, the collagen fiber content in the negative control group was significantly reduced, indicating that the stimulation conditions of this experiment were effective.
- Compared with the negative control group, the collagen fiber content in the positive control group was significantly increased, indicating that the positive control test was effective.
- Recollagen with a concentration of 0.2% significantly increased the collagen fiber content.
Compared with the negative control group, the collagen fiber content in the Recollagen group increased significantly, indicating that recombinant collagen can promote the regeneration of collagen fibers in skin tissue and has anti-aging effects.
Anti-Aging Ability Assessment 2
Result
Compared with before use, the overall wrinkle severity level was significantly improved after 2 and 4 weeks of continuous use of the test product (P<0.05), with an improvement of 7.14% in 2 weeks and 23.50% in 4 weeks.
Result:
Compared with before use, the total skin elasticity R2 was significantly improved after continuous use of the test product for 2 weeks and 4 weeks (P<0.05), with an improvement of 6.15% in 2 weeks and 13.85% in 4 weeks.
Result:
Compared with before use, transepidermal water loss was significantly improved after continuous use of the test product for 2 weeks and 4 weeks (P<0.05), with an improvement of 23.43% in 2 weeks and 37.30% in 4 weeks.
Case Study 1